SBS Publications [April 2017]

28 Apr 2017

Selected recent and ‘in press’ publications from across the School of Biological Sciences.

Cell Matrix Biology and Regenerative Medicine

• Parente, R., Clark, S.J., Inforzato, I. & Day, A.J. 2017. Complement factor H in host defense and immune evasion. Cell. Mol. Life Sci.74, 1605-1624.
• Milani, A.H., Fielding, L.A., Greensmith, P., Saunders, B.R., Adlam, D.J., Freemont, A.J., Hoyland, J.A., Hodson, N.W., Elsawy, M.A., Miller, A.F. and Ratcliffe, L.P., 2017. Anisotropic pH-responsive Hydrogels containing Soft or Hard Rod-like Particles Assembled using Low Shear. Chemistry of Materials, 29(7), pp.3100-3110.

In Press

• Richardson SM*, Ludwinski FE, Gnanalingham KK, Atkinson R, Freemont AJ, Hoyland JA. Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration. Accepted at Nature Scientific Reports.
• Swinton K, Hoyland JA, Richardson SM*. Effects of replicative senescence on donor-matched bone marrow and adipose-derived MSCs: implications for musculoskeletal tissue engineering. Accepted at Stem Cells International.

Infection, Immunity and Respiratory Medicine

• Moore, C.B., Novak-Frazer, L., Muldoon, E., Dunn, K.W., Masania, R., Richardson, M.D. and Rautemaa-Richardson, R., 2017. First isolation of the pan-azole-resistant Aspergillus fumigatus cyp51A TR46/Y121F/T289A mutant in a UK patient. International Journal of Antimicrobial Agents. http://www.ijaaonline.com/article/S0924-8579(17)30041-9/abstract
• Stone, J. P., J, Mohamud, M., Amin, K., Critchley, W. R., Edge, R. J., Clancy, M. J., Ball, A. L., Fildes, J.E. 2017. Characterising the early inflammatory contribution of the donor kidney following reperfusion. Accepted in Nephrology, dialysis and transplantation: official publication of the European Dialysis and Transplant Association-European Renal Association. doi: 10.1093/ndt/gfw464. [Epub ahead of print]
• Montacute, R., Foley, K., Forman, R., Else, K.J., Cruickshank, S.M. and Allan, S.M., 2017. Enhanced susceptibility of triple transgenic Alzheimer’s disease (3xTg-AD) mice to acute infection. Journal of Neuroinflammation, 14(1), p.50. https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-017-0826-5
• Withers, S.B., Forman, R., Meza-Perez, S., Sorobetea, D., Sitnik, K., Hopwood, T., Lawrence, C.B., Agace, W.W., Else, K.J., Heagerty, A.M. and Svensson-Frej, M., 2017. Eosinophils are key regulators of perivascular adipose tissue and vascular functionality. Scientific Reports, 7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356000/
• Lopes, F.B., Bálint, Š., Valvo, S., Felce, J.H., Hessel, E.M., Dustin, M.L. and Davis, D.M., 2017. Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages. J Cell Biol, pp.jcb-201608094. http://jcb.rupress.org/content/early/2017/03/10/jcb.201608094
  A commentary on the above paper can be found online: http://jcb.rupress.org/content/early/2017/03/21/jcb.201702028
• Morgan, D.J. and Davis, D.M.D., 2017. Distinct effects of dexamethasone on human Natural Killer cell responses dependent on cytokines. Frontiers in Immunology, 8, p.432. http://journal.frontiersin.org/article/10.3389/fimmu.2017.00432/full
• Partridge, F.A., Murphy, E.A., Willis, N.J., Bataille, C.J., Forman, R., Heyer-Chauhan, N., Marinič, B., Sowood, D.J., Wynne, G.M., Else, K.J. and Russell, A.J., 2017. Dihydrobenz [e][1, 4] oxazepin-2 (3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo. PLOS Neglected Tropical Diseases, 11(2), p.e0005359.
  http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005359 Trichuris was also featured on the PLOS NTDs cover page.

In press

• Stone, J., Ball, A. L., Critchley, W. R., Major, T., Edge, R. J., Amin, K., Clancy, M., Fildes, J. E. Ex vivo normothermic perfusion reduces kidney immunogenicity prior to transplantation via removal of passenger leukocytes. Accepted in Kidney International Reports.
• Dholakia, S., Fildes, J. E., Friend, P. J. The use of kinase inhibitors in transplantation. Accepted in Transplantation Reviews.
• Entwistle, T. R., Green, A. C., Fildes, J. E., Miura, K. Adherence to randomised Mediterranean or low fat diets among heart and lung transplant recipients: a 12-month pilot study. Accepted in Journal of the Academy of Nutrition.

Neuroscience and Experimental Psychology

• Anderson, I.M., Blamire, A., Branton, T., Clark, R., Downey, D., Dunn, G., Easton, A., Elliott, R., Elwell, C., Hayden, K. and Holland, F., 2017. Ketamine augmentation of electroconvulsive therapy to improve neuropsychological and clinical outcomes in depression (Ketamine-ECT): a multicentre, double-blind, randomised, parallel-group, superiority trial. The Lancet Psychiatry.
• Coleman, G. and Canal, M.M., 2017. Postnatal light effects on pup stress axis development are independent of maternal behavior. Frontiers in Neuroscience, 11. https://doi.org/10.3389/fnins.2017.00046

In Press

• Jackson, R.L., Bajada, C.J., Rice, G.E., Cloutman, L.L. and Ralph, M.A.L., 2017. An emergent functional parcellation of the temporal cortex. NeuroImage. http://doi.org/10.1016/j.neuroimage.2017.04.024
• Bajada, C.J., Jackson, R.L., Haroon, H.A., Azadbakht, H., Parker, G.J., Ralph, M.A.L. and Cloutman, L.L., 2017. A Graded Tractographic Parcellation of the Temporal Lobe. NeuroImage. http://doi.org/10.1016/j.neuroimage.2017.04.016
  

Molecular and Cellular Function

• Francavilla, C., Lupia, M., Tsafou, K., Villa, A., Kowalczyk, K., Jersie-Christensen, R.R., Bertalot, G., Confalonieri, S., Brunak, S., Jensen, L.J. and Cavallaro, U., 2017. Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer.Cell Reports, 18(13), pp.3242-3256. http://doi.org/10.1016/j.celrep.2017.03.015

In press

• Jennings, M.D., Kershaw, C.J., Adomavicius, T. and Pavitt, G.D., 2017. Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes. eLife, 6, p.e24542. doi: http://dx.doi.org/10.7554/eLife.24542

Musculoskeletal and Dermatological Sciences

• Langton, A.K., Graham, H.K., McConnell, J.C., Sherratt, M.J., Griffiths, C.E.M. and Watson, R.E.B., 2017. Organisation of the dermal matrix impacts the biomechanical properties of skin. British Journal of Dermatology. [Epub ahead of print] http://onlinelibrary.wiley.com/doi/10.1111/bjd.15353/full